By Joshua O. Benditt, et al. American College of Chest Physicians
Directly from the ACCP serious Care medication Board evaluate 2009 path, this article covers each subject in a concise, easy-to-use structure. Use as a self-study source to organize for the serious care medication subspecialty board exam.
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Extra info for ACCP Critical Care Medicine Board Review, 20th Edition
Recurrent use of fluconazole in HIV-infected patients has been associated with an increasing number of reports of Candida spp resistant to this agent. 67 28 Aspergillus spp As is the case with Candida, Aspergillus may cause infection in patients with defects in either neutrophil function or cell-mediated immunity. In addition to being a nosocomial pathogen, infection with this agent may represent reactivation disease. This may be especially notable in patients who have received a bone marrow transplant or solid organ transplant.
When bound by properdin, the C3 convertase is stabilized and can then cleave more C3 to generate more C3b, with a resultant amplification of the alternative complement pathway. 22 There are four clinically relevant situations within the category of defective humoral immunity: (1) disorders of immunoglobulin production; (2) asplenia or hyposplenic states; (3) hypocomplementemia; and (4) impaired neutralization of toxins. The major clinical situations that result in disorders of immunoglobulin production are summarized in Table 3.
43 complication of this localization. Bacteremia is another common presentation, with cerebritis or brain abscess being less frequent. 47 For penicillin-allergic patients, trimethoprimsulfamethoxazole is possibly effective. Extremely noteworthy is that cephalosporin therapy has no role in treating infection caused by Listeria. Because of the intracellular location of the organisms, 3 weeks of therapy is recommended for serious infections. Listeria monocytogenes These filamentous aerobic Gram-positive rods are weakly acid-fast and characteristically produce disease in patients who have lymphoreticular neoplasms or have received long-term corticosteroid therapy.
ACCP Critical Care Medicine Board Review, 20th Edition by Joshua O. Benditt, et al. American College of Chest Physicians